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Search Results for " interleukin 17a "
Targets Recommended: IL Receptor

9

抑制剂 & 化合物

22

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T9448 IL-17A inhibitor 1

IL Receptor Immunology/Inflammation
IL-17A inhibitor 1 是 IL-17A 的抑制剂,在alphalisa assay 中的IC50为 <9.45 nM。IL-17A inhibitor 1抑制HT-29 细胞的 IC50 值为 9.3 nM。
T11635 IL-17A antagonist 1

IL Receptor Immunology/Inflammation
IL-17A antagonist 1 是一种 IL-17A 拮抗剂,可用于研究和白介素相关的炎症和免疫疾病。
T38105 Ixekizumab

LY2439821

IL Receptor; Interleukin Immunology/Inflammation
Ixekizumab (LY2439821) 是一种人源化 IgG4 单克隆抗体,可选择性结合和中和白细胞介素 IL-17A ,Kd 值<3 pM。Ixekizumab 科阻断 IL-17A 与 IL-17RA 的结合,但不与其他 IL-17 家族成员结合。Ixekizumab 用于治疗中重度斑块型银屑病、银屑病关节炎和牛皮癣。
T4403 AX-024 hydrochloride

AX-024 HCl

IL Receptor; TNF; COX; IFNAR; Interleukin Apoptosis; Immunology/Inflammation; Neuroscience
AX-024 hydrochloride (AX-024 HCl) 是一种细胞因子释放抑制剂,可强烈抑制 IL-6、TNFα、IFN-γ、IL-10 和 IL-17A 的产生。它是口服可利用的 TCR-Nck 相互作用抑制剂,可选择性地抑制 TCR 触发的 T 细胞活化。它通过靶向 SH3结构域调节细胞信号传导,具有低毒、高效和高选择性的特点。
T76256 Erepdekinra

Erepdekinra 是一种白细胞介素-17A (IL-17A) 受体拮抗剂。
T76953 Xeligekimab

Xeligekimab (GR 1501)为一种针对人白细胞介素17A (IL-17A) 的人源化单克隆抗体,可抑制促炎级联反应。
T76797 Anti-Human IL-17A

Anti-HumanIL-17A 是一种全人抗白细胞介素 17A 单克隆抗体。Anti-HumanIL-17A 可用于银屑病发病机制研究。
T76823 Perakizumab

Perakizumab (RG4934)为针对IL-17A(Interleukin Related)的人源化IgG1κ单克隆抗体。适用于自身免疫性疾病(例如银屑病关节炎)的研究。
T76885 Sonelokimab

Sonelokimab (ALX 0761; M 1095) 是三价纳米抗体,特异性结合人白介素(IL)-17A、IL-17F及人血清白蛋白VHH,由单价骆驼来源纳米抗体构成,展现于斑块型银屑病研究中的应用潜力。

化合物

IL-17A inhibitor 1
Cat.No: T9448
Synonym:
Target: IL Receptor
IL-17A antagonist 1
Cat.No: T11635
Synonym:
Target: IL Receptor
Ixekizumab
Cat.No: T38105
Synonym: LY2439821
Target: IL Receptor, Interleukin
AX-024 hydrochloride
Cat.No: T4403
Synonym: AX-024 HCl
Target: IL Receptor, TNF, COX, IFNAR, Interleukin
Erepdekinra
Cat.No: T76256
Synonym:
Target:
Xeligekimab
Cat.No: T76953
Synonym:
Target:
Anti-Human IL-17A
Cat.No: T76797
Synonym:
Target:
Perakizumab
Cat.No: T76823
Synonym:
Target:
Sonelokimab
Cat.No: T76885
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-00470 IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His)

interleukin 17A,IL-17,IL-17A,IL17...

Human HEK293 Cells
IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is NP_002181.1&NP_443104.1.
TMPY-00053 IL-17A & IL-17F Heterodimer Protein, Human, Recombinant

CTLA8,IL17,IL-17,IL-17A,interleukin 17...

Human E. coli
IL-17A & IL-17F Heterodimer Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 30.7 kDa and the accession number is Q16552&NP_443104.1.
TMPY-02900 IL-17A Protein, Mouse, Recombinant

IL-17A,Ctla8,Ctla-8,interleukin 17A

Mouse E. coli
IL-17A Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.5 kDa and the accession number is Q62386.
TMPJ-01172 IL-17 Protein, Mouse, Recombinant (His)

CTLA8,IL-17,IL-17A,Interleukin-17A

Mouse HEK293 Cells
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A, respectively. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumato...
TMPY-02886 IL-17A Protein, Human, Recombinant

IL-17,白细胞介素,interleukin 17A,CTLA8,白介素,IL17...

Human E. coli
IL-17A Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is Q16552.
TMPY-05342 IL-17A Protein, Cynomolgus, Recombinant

interleukin 17A

Cynomolgus Baculovirus Insect Cells
IL-17A Protein, Cynomolgus, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 15.1 kDa and the accession number is A0A2K5TTB0.
TMPY-04728 IL-17A & IL-17F Heterodimer Protein, Rhesus, Recombinant (His)

interleukin 17A

Rhesus HEK293 Cells
IL-17A & IL-17F Heterodimer Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.5 kDa and the accession number is XP_001106391.1&NP_001248216.1.
TMPY-04710 IL-17 Protein, Rhesus, Recombinant

白介素,白细胞介素,interleukin 17A

Rhesus Baculovirus Insect Cells
IL-17 Protein, Rhesus, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 15.1 kDa and the accession number is A0A8J8YJF1.
TMPY-04888 IL-17 Protein, Rabbit, Recombinant

白细胞介素,白介素,interleukin 17A

Rabbit E. coli
IL-17 Protein, Rabbit, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is G1SLF2.
TMPY-03906 IL-17 Protein, Canine, Recombinant

白细胞介素,interleukin 17A,白介素

Canine E. coli
IL-17 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.2 kDa and the accession number is C6L8D7.
TMPY-04609 IL-17 Protein, Rabbit, Recombinant (His)

白细胞介素,白介素,interleukin 17A

Rabbit Baculovirus Insect Cells
IL-17 Protein, Rabbit, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is G1SLF2.
TMPY-03931 IL-17 Protein, Marmoset, Recombinant

interleukin 17A,白介素,白细胞介素

Marmoset E. coli
IL-17 Protein, Marmoset, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.4 kDa and the accession number is A5HJM0.
TMPY-04332 IL-17A Protein, Human, Recombinant (T26A, His)

CTLA-8,CTLA8,IL-17A,interleukin 17A

Human Baculovirus Insect Cells
IL-17A Protein, Human, Recombinant (T26A, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.2 kDa and the accession number is Q16552.
TMPY-05183 IL-17A Protein, Human, Recombinant, Biotinylated

interleukin 17A,IL-17,白细胞介素,白介素,IL17,CTLA8...

Human E. coli
IL-17A Protein, Human, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is Q16552.
TMPY-03568 IL-17A Protein, Human, Recombinant (His)

CTLA-8,CTLA8,白介素,interleukin 17A,IL17,IL-<...

Human P. pastoris (Yeast)
IL-17A Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 17.3 kDa and the accession number is Q16552.
TMPK-01036 IL-17A Protein, Mouse, Recombinant (His & Avi)

interleukin 17A,IL17A,CTLA-8,IL17...

Mouse HEK293 Cells
IL-17A Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the accession number is Q62386-1.
TMPJ-01444 IL-17A Protein, Cynomolgus, Recombinant (His)

CTLA-8,CTLA8,IL17A,IL-17,IL-17A,Cytotoxic ...

Cynomolgus HEK293 Cells
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synt...
TMPK-01266 IL-17A Protein, Cynomolgus, Recombinant (His & Avi)

IL17,interleukin 17A,IL17A,IL-17C...

Cynomolgus HEK293 Cells
IL-17A Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is A0A2K5TTB0.
TMPK-00975 IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated

IL-17CTLA-8,interleukin 17A,CTLA-8,IL17,IL...

Human HEK293 Cells
IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is Q16552-1.
TMPK-01037 IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated

IL17A,interleukin 17A,IL17,CTLA-8...

Mouse HEK293 Cells
IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the accession number is Q62386-1.
TMPJ-00046 IL-17F Protein, Human, Recombinant

IL17F,白介素,IL-17F,Interleukin-17F,白细胞介素,Cytokine ML-...

Human E. coli
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage mat...
TMPK-00084 IL-17C Protein, Human, Recombinant (His & Avi)

IL-17C,Cytokine CX2,IL17C,CX2,IL-17CMGC126884

Human HEK293 Cells
Interleukin‑17C (IL‑17C) is a 15‑20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold. IL‑17C is Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by sig...

重组蛋白

IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His)
Cat.No: TMPY-00470
Species: Human
Expression System: HEK293 Cells
IL-17A & IL-17F Heterodimer Protein, Human, Recombinant
Cat.No: TMPY-00053
Species: Human
Expression System: E. coli
IL-17A Protein, Mouse, Recombinant
Cat.No: TMPY-02900
Species: Mouse
Expression System: E. coli
IL-17 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01172
Species: Mouse
Expression System: HEK293 Cells
IL-17A Protein, Human, Recombinant
Cat.No: TMPY-02886
Species: Human
Expression System: E. coli
IL-17A Protein, Cynomolgus, Recombinant
Cat.No: TMPY-05342
Species: Cynomolgus
Expression System: Baculovirus Insect Cells
IL-17A & IL-17F Heterodimer Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-04728
Species: Rhesus
Expression System: HEK293 Cells
IL-17 Protein, Rhesus, Recombinant
Cat.No: TMPY-04710
Species: Rhesus
Expression System: Baculovirus Insect Cells
IL-17 Protein, Rabbit, Recombinant
Cat.No: TMPY-04888
Species: Rabbit
Expression System: E. coli
IL-17 Protein, Canine, Recombinant
Cat.No: TMPY-03906
Species: Canine
Expression System: E. coli
IL-17 Protein, Rabbit, Recombinant (His)
Cat.No: TMPY-04609
Species: Rabbit
Expression System: Baculovirus Insect Cells
IL-17 Protein, Marmoset, Recombinant
Cat.No: TMPY-03931
Species: Marmoset
Expression System: E. coli
IL-17A Protein, Human, Recombinant (T26A, His)
Cat.No: TMPY-04332
Species: Human
Expression System: Baculovirus Insect Cells
IL-17A Protein, Human, Recombinant, Biotinylated
Cat.No: TMPY-05183
Species: Human
Expression System: E. coli
IL-17A Protein, Human, Recombinant (His)
Cat.No: TMPY-03568
Species: Human
Expression System: P. pastoris (Yeast)
IL-17A Protein, Mouse, Recombinant (His & Avi)
Cat.No: TMPK-01036
Species: Mouse
Expression System: HEK293 Cells
IL-17A Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-01444
Species: Cynomolgus
Expression System: HEK293 Cells
IL-17A Protein, Cynomolgus, Recombinant (His & Avi)
Cat.No: TMPK-01266
Species: Cynomolgus
Expression System: HEK293 Cells
IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00975
Species: Human
Expression System: HEK293 Cells
IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01037
Species: Mouse
Expression System: HEK293 Cells
IL-17F Protein, Human, Recombinant
Cat.No: TMPJ-00046
Species: Human
Expression System: E. coli
IL-17C Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00084
Species: Human
Expression System: HEK293 Cells
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