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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9448 |
IL-17A inhibitor 1
|
IL Receptor | Immunology/Inflammation |
IL-17A inhibitor 1 是 IL-17A 的抑制剂,在alphalisa assay 中的IC50为 <9.45 nM。IL-17A inhibitor 1抑制HT-29 细胞的 IC50 值为 9.3 nM。 | |||
T11635 |
IL-17A antagonist 1
|
IL Receptor | Immunology/Inflammation |
IL-17A antagonist 1 是一种 IL-17A 拮抗剂,可用于研究和白介素相关的炎症和免疫疾病。 | |||
T38105 |
Ixekizumab
LY2439821 |
IL Receptor; Interleukin | Immunology/Inflammation |
Ixekizumab (LY2439821) 是一种人源化 IgG4 单克隆抗体,可选择性结合和中和白细胞介素 IL-17A ,Kd 值<3 pM。Ixekizumab 科阻断 IL-17A 与 IL-17RA 的结合,但不与其他 IL-17 家族成员结合。Ixekizumab 用于治疗中重度斑块型银屑病、银屑病关节炎和牛皮癣。 | |||
T4403 |
AX-024 hydrochloride
AX-024 HCl |
IL Receptor; TNF; COX; IFNAR; Interleukin | Apoptosis; Immunology/Inflammation; Neuroscience |
AX-024 hydrochloride (AX-024 HCl) 是一种细胞因子释放抑制剂,可强烈抑制 IL-6、TNFα、IFN-γ、IL-10 和 IL-17A 的产生。它是口服可利用的 TCR-Nck 相互作用抑制剂,可选择性地抑制 TCR 触发的 T 细胞活化。它通过靶向 SH3结构域调节细胞信号传导,具有低毒、高效和高选择性的特点。 | |||
T76256 |
Erepdekinra
|
||
Erepdekinra 是一种白细胞介素-17A (IL-17A) 受体拮抗剂。 | |||
T76953 | Xeligekimab | ||
Xeligekimab (GR 1501)为一种针对人白细胞介素17A (IL-17A) 的人源化单克隆抗体,可抑制促炎级联反应。 | |||
T76797 | Anti-Human IL-17A | ||
Anti-HumanIL-17A 是一种全人抗白细胞介素 17A 单克隆抗体。Anti-HumanIL-17A 可用于银屑病发病机制研究。 | |||
T76823 | Perakizumab | ||
Perakizumab (RG4934)为针对IL-17A(Interleukin Related)的人源化IgG1κ单克隆抗体。适用于自身免疫性疾病(例如银屑病关节炎)的研究。 | |||
T76885 | Sonelokimab | ||
Sonelokimab (ALX 0761; M 1095) 是三价纳米抗体,特异性结合人白介素(IL)-17A、IL-17F及人血清白蛋白VHH,由单价骆驼来源纳米抗体构成,展现于斑块型银屑病研究中的应用潜力。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00470 |
IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His)
interleukin 17A,IL-17,IL-17A,IL17... |
Human | HEK293 Cells |
IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is NP_002181.1&NP_443104.1. | |||
TMPY-00053 |
IL-17A & IL-17F Heterodimer Protein, Human, Recombinant
CTLA8,IL17,IL-17,IL-17A,interleukin 17... |
Human | E. coli |
IL-17A & IL-17F Heterodimer Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 30.7 kDa and the accession number is Q16552&NP_443104.1. | |||
TMPY-02900 |
IL-17A Protein, Mouse, Recombinant
IL-17A,Ctla8,Ctla-8,interleukin 17A |
Mouse | E. coli |
IL-17A Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.5 kDa and the accession number is Q62386. | |||
TMPJ-01172 |
IL-17 Protein, Mouse, Recombinant (His)
CTLA8,IL-17,IL-17A,Interleukin-17A |
Mouse | HEK293 Cells |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A, respectively. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumato... | |||
TMPY-02886 |
IL-17A Protein, Human, Recombinant
IL-17,白细胞介素,interleukin 17A,CTLA8,白介素,IL17... |
Human | E. coli |
IL-17A Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is Q16552. | |||
TMPY-05342 |
IL-17A Protein, Cynomolgus, Recombinant
interleukin 17A |
Cynomolgus | Baculovirus Insect Cells |
IL-17A Protein, Cynomolgus, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 15.1 kDa and the accession number is A0A2K5TTB0. | |||
TMPY-04728 |
IL-17A & IL-17F Heterodimer Protein, Rhesus, Recombinant (His)
interleukin 17A |
Rhesus | HEK293 Cells |
IL-17A & IL-17F Heterodimer Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.5 kDa and the accession number is XP_001106391.1&NP_001248216.1. | |||
TMPY-04710 |
IL-17 Protein, Rhesus, Recombinant
白介素,白细胞介素,interleukin 17A |
Rhesus | Baculovirus Insect Cells |
IL-17 Protein, Rhesus, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 15.1 kDa and the accession number is A0A8J8YJF1. | |||
TMPY-04888 |
IL-17 Protein, Rabbit, Recombinant
白细胞介素,白介素,interleukin 17A |
Rabbit | E. coli |
IL-17 Protein, Rabbit, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is G1SLF2. | |||
TMPY-03906 |
IL-17 Protein, Canine, Recombinant
白细胞介素,interleukin 17A,白介素 |
Canine | E. coli |
IL-17 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.2 kDa and the accession number is C6L8D7. | |||
TMPY-04609 |
IL-17 Protein, Rabbit, Recombinant (His)
白细胞介素,白介素,interleukin 17A |
Rabbit | Baculovirus Insect Cells |
IL-17 Protein, Rabbit, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is G1SLF2. | |||
TMPY-03931 |
IL-17 Protein, Marmoset, Recombinant
interleukin 17A,白介素,白细胞介素 |
Marmoset | E. coli |
IL-17 Protein, Marmoset, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.4 kDa and the accession number is A5HJM0. | |||
TMPY-04332 |
IL-17A Protein, Human, Recombinant (T26A, His)
CTLA-8,CTLA8,IL-17A,interleukin 17A |
Human | Baculovirus Insect Cells |
IL-17A Protein, Human, Recombinant (T26A, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.2 kDa and the accession number is Q16552. | |||
TMPY-05183 |
IL-17A Protein, Human, Recombinant, Biotinylated
interleukin 17A,IL-17,白细胞介素,白介素,IL17,CTLA8... |
Human | E. coli |
IL-17A Protein, Human, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is Q16552. | |||
TMPY-03568 |
IL-17A Protein, Human, Recombinant (His)
CTLA-8,CTLA8,白介素,interleukin 17A,IL17,IL-<... |
Human | P. pastoris (Yeast) |
IL-17A Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 17.3 kDa and the accession number is Q16552. | |||
TMPK-01036 |
IL-17A Protein, Mouse, Recombinant (His & Avi)
interleukin 17A,IL17A,CTLA-8,IL17... |
Mouse | HEK293 Cells |
IL-17A Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the accession number is Q62386-1. | |||
TMPJ-01444 |
IL-17A Protein, Cynomolgus, Recombinant (His)
CTLA-8,CTLA8,IL17A,IL-17,IL-17A,Cytotoxic ... |
Cynomolgus | HEK293 Cells |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synt... | |||
TMPK-01266 |
IL-17A Protein, Cynomolgus, Recombinant (His & Avi)
IL17,interleukin 17A,IL17A,IL-17C... |
Cynomolgus | HEK293 Cells |
IL-17A Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is A0A2K5TTB0. | |||
TMPK-00975 |
IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated
IL-17CTLA-8,interleukin 17A,CTLA-8,IL17,IL... |
Human | HEK293 Cells |
IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is Q16552-1. | |||
TMPK-01037 |
IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated
IL17A,interleukin 17A,IL17,CTLA-8... |
Mouse | HEK293 Cells |
IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the accession number is Q62386-1. | |||
TMPJ-00046 |
IL-17F Protein, Human, Recombinant
IL17F,白介素,IL-17F,Interleukin-17F,白细胞介素,Cytokine ML-... |
Human | E. coli |
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage mat... | |||
TMPK-00084 |
IL-17C Protein, Human, Recombinant (His & Avi)
IL-17C,Cytokine CX2,IL17C,CX2,IL-17CMGC126884 |
Human | HEK293 Cells |
Interleukin‑17C (IL‑17C) is a 15‑20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold. IL‑17C is Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by sig... |